Well, since Santana is a lesbian, it would never truly work out. However, I do think that they had great chemistry during Smooth Criminal and would love to see them as frenimies!
I've kinda got an unbalanced opinion of this ship. Sometimes I wanna sock Sebastian in the face. Yet, I can't help but be drawn to him. It was the same thing with Jesse. But then I saw spring awakening, and then it was like St.Berry became my second kidney. >< We were besties for almost a full two years. I still love em but Kinn is my current new found love <3